Mitochondrial ATP-synthase activity in cardiomyocytes after aerobic-anaerobic metabolic transition.

@article{Noll1992MitochondrialAA,
  title={Mitochondrial ATP-synthase activity in cardiomyocytes after aerobic-anaerobic metabolic transition.},
  author={Th Noll and Anna Koop and Hans Michael Piper},
  journal={The American journal of physiology},
  year={1992},
  volume={262 5 Pt 1},
  pages={C1297-303}
}
It has been hypothesized that, in oxygen-depleted myocardial cells, mitochondria are depolarized and the F1,F0-proton adenosinetriphosphatase (ATPase) catalyzes net ATP hydrolysis when the cells exhibit the signs of an aerobic-anaerobic metabolic transition, which are increased lactate formation and decline in high-energy phosphate reserves [W. Rouslin, C. W. Broge, and I. L. Grupp. Am. J. Physiol. 259 (Heart Circ. Physiol. 28): H1759-H1766, 1990]. This hypothesis was tested by incubating… CONTINUE READING
11 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…