Mitochondria selective S-nitrosation by mitochondria-targeted S-nitrosothiol protects against post-infarct heart failure in mouse hearts

@inproceedings{Methner2014MitochondriaSS,
  title={Mitochondria selective S-nitrosation by mitochondria-targeted S-nitrosothiol protects against post-infarct heart failure in mouse hearts},
  author={Carmen Methner and Edward T. Chouchani and Guido Buonincontri and Victoria R. Pell and Stephen J. Sawiak and Michael P Murphy and Thomas Krieg},
  booktitle={European journal of heart failure},
  year={2014}
}
AIMS Recently it has been shown that the mitochondria-targeted S-nitrosothiol MitoSNO protects against acute ischaemia/reperfusion (IR) injury by inhibiting the reactivation of mitochondrial complex I in the first minutes of reperfusion of ischaemic tissue, thereby preventing free radical formation that underlies IR injury. However, it remains unclear how… CONTINUE READING