Mitochondria-rich, proton-secreting epithelial cells.

@article{Brown1996MitochondriarichPE,
  title={Mitochondria-rich, proton-secreting epithelial cells.},
  author={Dennis L. Brown and Sylvie Breton},
  journal={The Journal of experimental biology},
  year={1996},
  volume={199 Pt 11},
  pages={2345-58}
}
Several transporting epithelia in vertebrates and invertebrates contain cells that are specialized for proton or bicarbonate secretion. These characteristic 'mitochondria-rich' (MR) cells have several typical features, the most important of which is an extremely high expression of a vacuolar-type proton-pumping ATPase (H+V-ATPase) both on intracellular vesicles and on specific domains of their plasma membrane. Physiological modulation of proton secretion is achieved by recycling the H+V-ATPase… CONTINUE READING

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