Mitochondria mediate septin cage assembly to promote autophagy of Shigella

Abstract

Septins, cytoskeletal proteins with well-characterised roles in cytokinesis, form cage-like structures around cytosolic Shigella flexneri and promote their targeting to autophagosomes. However, the processes underlying septin cage assembly, and whether they influence S. flexneri proliferation, remain to be established. Using single-cell analysis, we show… (More)
DOI: 10.15252/embr.201541832

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