Mitochondria as a Pharmacological Target
@article{Szewczyk2002MitochondriaAA, title={Mitochondria as a Pharmacological Target}, author={Adam Szewczyk and Lech Wojtczak}, journal={Pharmacological Reviews}, year={2002}, volume={54}, pages={101 - 127} }
Mitochondria play a central role in energy metabolism within the cell. Mitochondrial dysfunctions lead to various neurodegenerative disorders and to the so-called “mitochondrial diseases”. A vast amount of evidence points to the implication of mitochondria in such complex processes as apoptosis and cardioprotection. The purpose of this review is to present a recent state of our knowledge and understanding of the action of various therapeutically applied substances on mitochondria. These include…
525 Citations
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