Mitochondria as a Pharmacological Target

  title={Mitochondria as a Pharmacological Target},
  author={Adam Szewczyk and Lech Wojtczak},
  journal={Pharmacological Reviews},
  pages={101 - 127}
Mitochondria play a central role in energy metabolism within the cell. Mitochondrial dysfunctions lead to various neurodegenerative disorders and to the so-called “mitochondrial diseases”. A vast amount of evidence points to the implication of mitochondria in such complex processes as apoptosis and cardioprotection. The purpose of this review is to present a recent state of our knowledge and understanding of the action of various therapeutically applied substances on mitochondria. These include… 

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