Mitochondria are involved in the neurogenic neuroprotection conferred by stimulation of cerebellar fastigial nucleus.

@article{Zhou2005MitochondriaAI,
  title={Mitochondria are involved in the neurogenic neuroprotection conferred by stimulation of cerebellar fastigial nucleus.},
  author={Ping Zhou and Liping Qian and Theresa X. Zhou and C Iadecola},
  journal={Journal of neurochemistry},
  year={2005},
  volume={95 1},
  pages={221-9}
}
Activation of neural pathways originating in the cerebellar fastigial nucleus (FN) protects the brain from the deleterious effects of cerebral ischemia and excitotoxicity, a phenomenon termed central neurogenic neuroprotection. The neuroprotection is, in part, mediated by suppression of apoptosis. We sought to determine whether FN stimulation exerts its anti-apoptotic effect through mitochondrial mechanisms. Mitochondria were isolated from the cerebral cortex of rats in which the FN was… CONTINUE READING

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