Mitochondria Know No Boundaries: Mechanisms and Functions of Intercellular Mitochondrial Transfer

@inproceedings{Torralba2016MitochondriaKN,
  title={Mitochondria Know No Boundaries: Mechanisms and Functions of Intercellular Mitochondrial Transfer},
  author={Daniel Torralba and Francesc Baixauli and Francisco S{\'a}nchez-Madrid},
  booktitle={Front. Cell Dev. Biol.},
  year={2016}
}
Mitochondria regulate multiple cell processes, including calcium signaling, apoptosis and cell metabolism. Mitochondria contain their own circular genome encoding selected subunits of the oxidative phosphorylation complexes. Recent findings reveal that, in addition to being maternally inherited, mitochondria can traverse cell boundaries and thus be horizontally transferred between cells. Although, the physiological relevance of this phenomenon is still under debate, mitochondria uptake rescues… CONTINUE READING
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