Mitochondria: a therapeutic target in acute kidney injury.

@article{Ishimoto2016MitochondriaAT,
  title={Mitochondria: a therapeutic target in acute kidney injury.},
  author={Yu Ishimoto and Reiko Inagi},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2016},
  volume={31 7},
  pages={1062-9}
}
Acute kidney injury (AKI) is a common clinical entity that is associated with high mortality and morbidity. It is a risk factor for the development and progression of chronic kidney disease. Presently, no effective treatment for AKI is available, and novel therapeutic approaches are desperately needed. Accumulating evidence highlights mitochondrial dysfunction as an important factor in the pathogenesis of AKI. Recent advances in our understanding of the molecules involved in mitochondrial… CONTINUE READING

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