Mitochondria: a target for myocardial protection.

  title={Mitochondria: a target for myocardial protection.},
  author={M-Saadeh Suleiman and Andrew Philip Halestrap and Elinor J. Griffiths},
  journal={Pharmacology & therapeutics},
  volume={89 1},
The ischemic heart requires reperfusion using clinical interventions, such as coronary artery bypass graft surgery, in order to recover. Despite recent developments in myocardial protection techniques, reperfusion damage still occurs, and significant morbidity remains a problem. Therefore, the search continues for techniques that will limit myocardial damage and that will enhance recovery upon reperfusion. Mitochondria are known to be intimately involved in the processes that lead to cell death… CONTINUE READING
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