Mitochondria: a hub of redox activities and cellular distress control

  title={Mitochondria: a hub of redox activities and cellular distress control},
  author={Poonam Kakkar and Brijesh Kumar Singh},
  journal={Molecular and Cellular Biochemistry},
In their reductionist approach in unraveling phenomena inside the cell, scientists in recent times have focused attention to mitochondria. An organelle with peculiar evolutionary history and organization, it is turning out to be an important cell survival switch. Besides controlling bioenergetics of a cell it also has its own genetic machinery which codes 37 genes. It is a major source of generation of reactive oxygen species, acts as a safety device against toxic increases of cytosolic Ca2… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 210 references

Aging, lipid modifications and phospholipases—new concepts

Ageing Research Reviews • 2003
View 10 Excerpts
Highly Influenced

The mitochondrial permeability transition.

Biochimica et biophysica acta • 1995
View 7 Excerpts
Highly Influenced

physiologic consequences and potential for a role in ageing

Melov S Mitochondrial oxidative stress
Ann NY Acad Sci 908:219–225 Mol Cell Biochem • 2007
View 4 Excerpts
Highly Influenced

Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism.

The international journal of biochemistry & cell biology • 2005
View 3 Excerpts
Highly Influenced

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