Mitochondria: a hub of redox activities and cellular distress control

@article{Kakkar2007MitochondriaAH,
  title={Mitochondria: a hub of redox activities and cellular distress control},
  author={Poonam Kakkar and Brijesh Kumar Singh},
  journal={Molecular and Cellular Biochemistry},
  year={2007},
  volume={305},
  pages={235-253}
}
In their reductionist approach in unraveling phenomena inside the cell, scientists in recent times have focused attention to mitochondria. An organelle with peculiar evolutionary history and organization, it is turning out to be an important cell survival switch. Besides controlling bioenergetics of a cell it also has its own genetic machinery which codes 37 genes. It is a major source of generation of reactive oxygen species, acts as a safety device against toxic increases of cytosolic Ca2… CONTINUE READING
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