Mitochondria, oxygen free radicals, and apoptosis.

@article{Raha2001MitochondriaOF,
  title={Mitochondria, oxygen free radicals, and apoptosis.},
  author={Sandeep Raha and B. H. Robinson},
  journal={American journal of medical genetics},
  year={2001},
  volume={106 1},
  pages={
          62-70
        }
}
Reactive oxygen species (ROS) generated by mitochondria are produced as by-products of normal oxidative metabolism. The fate of these species is governed by a number of factors that vary from tissue to tissue in mammals and may be involved in the pathogenesis of disease. Reactive oxygen species are also invoked as agents that are important in the processes which become active in cells undergoing apoptosis. Integration of knowledge surrounding these different aspects of ROS generation is… CONTINUE READING
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