Mitochondria, oxygen free radicals, and apoptosis.

  title={Mitochondria, oxygen free radicals, and apoptosis.},
  author={Sandeep Raha and B. H. Robinson},
  journal={American journal of medical genetics},
  volume={106 1},
Reactive oxygen species (ROS) generated by mitochondria are produced as by-products of normal oxidative metabolism. The fate of these species is governed by a number of factors that vary from tissue to tissue in mammals and may be involved in the pathogenesis of disease. Reactive oxygen species are also invoked as agents that are important in the processes which become active in cells undergoing apoptosis. Integration of knowledge surrounding these different aspects of ROS generation is… CONTINUE READING
Highly Cited
This paper has 234 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 115 extracted citations

Mitochondrial OXPHOS Functions in R1H Rhabdomyosarcoma and Skeletal Muscles of the Rat

Neurochemical Research • 2006
View 4 Excerpts
Method Support
Highly Influenced

Heme oxygenase and carbon monoxide initiate homeostatic signaling

Journal of Molecular Medicine • 2007
View 6 Excerpts
Highly Influenced

234 Citations

Citations per Year
Semantic Scholar estimates that this publication has 234 citations based on the available data.

See our FAQ for additional information.