Mitochondria, endothelial cell function, and vascular diseases

  title={Mitochondria, endothelial cell function, and vascular diseases},
  author={Xiaoqiang Tang and Yu-Xuan Luo and Hou-zao Chen and De-Pei Liu},
  booktitle={Front. Physiol.},
Mitochondria are perhaps the most sophisticated and dynamic responsive sensing systems in eukaryotic cells. The role of mitochondria goes beyond their capacity to create molecular fuel and includes the generation of reactive oxygen species, the regulation of calcium, and the activation of cell death. In endothelial cells, mitochondria have a profound impact on cellular function under both healthy and diseased conditions. In this review, we summarize the basic functions of mitochondria in… CONTINUE READING
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