Mistletoe lectin modulates intestinal epithelial cell-derived cytokines and B cell IgA secretion.

@article{Lyu2009MistletoeLM,
  title={Mistletoe lectin modulates intestinal epithelial cell-derived cytokines and B cell IgA secretion.},
  author={S L Lyu and Won-Bong Park},
  journal={Archives of pharmacal research},
  year={2009},
  volume={32 3},
  pages={443-51}
}
A galactose- and N-acetyl-D-galactosamine-specific lectin (Viscum album L. var. coloratum agglutinin, VCA), which is known for its anti-cancer activity, was isolated from Korean mistletoe. In this study, IEC-6 rat intestinal epithelial cells and IM-9 human B-cells were cultured to determine the effect of VCA on cytokine and immunoglobulin (Ig) secretion. In lipopolysaccharide (LPS)-stimulated IEC-6 cells, VCA significantly shifted the interleukin (IL)-2, IL-5, IL-6, and tumor necrosis factor… CONTINUE READING
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