Misspecification of Cox regression models with composite endpoints


Researchers routinely adopt composite endpoints in multicenter randomized trials designed to evaluate the effect of experimental interventions in cardiovascular disease, diabetes, and cancer. Despite their widespread use, relatively little attention has been paid to the statistical properties of estimators of treatment effect based on composite endpoints… (More)
DOI: 10.1002/sim.5436

8 Figures and Tables


  • Presentations referencing similar topics