Missing value estimation in microarray data using coregulation and similarity of genes

@article{Paul2011MissingVE,
  title={Missing value estimation in microarray data using coregulation and similarity of genes},
  author={Amit Paul and Jaya Sil},
  journal={2011 World Congress on Information and Communication Technologies},
  year={2011},
  pages={705-710}
}
Microarray experiments usually generate multiple missing values in gene expression data sets due to several reasons. In the paper, a robust method has been proposed to estimate the missing values in microarray data using biological knowledge of the genes. Missing values are imputed based on the similarity in their characteristics patterns observed among the co-regulated genes. In this approach, first the microarray data are normalized and then the normalized data is discretized to measure… CONTINUE READING

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