Missing call bias in high-throughput genotyping

@article{Fu2008MissingCB,
  title={Missing call bias in high-throughput genotyping},
  author={Wenqing Fu and Yi Wang and Ying Wang and Rui Li and Rong Lin and Li Jin},
  journal={BMC Genomics},
  year={2008},
  volume={10},
  pages={106 - 106}
}
The advent of high-throughput and cost-effective genotyping platforms made genome-wide association (GWA) studies a reality. While the primary focus has been invested upon the improvement of reducing genotyping error, the problems associated with missing calls are largely overlooked. To probe into the effect of missing calls on GWAs, we demonstrated experimentally the prevalence and severity of the problem of missing call bias (MCB) in four genotyping technologies (Affymetrix 500 K SNP array… CONTINUE READING

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