Misregulated E-Cadherin Expression Associated with an Aggressive Brain Tumor Phenotype

@inproceedings{LewisTuffin2010MisregulatedEE,
  title={Misregulated E-Cadherin Expression Associated with an Aggressive Brain Tumor Phenotype},
  author={Laura J. Lewis-Tuffin and Fausto Rodr{\'i}guez and Caterina Giannini and Bernd Scheithauer and Brian Necela and Jann N. Sarkaria and Panos Z Anastasiadis},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Cadherins are essential components of the adherens junction complexes that mediate cell-cell adhesion and regulate cell motility. During tissue morphogenesis, changes in cadherin expression (known as cadherin switching) are a common mechanism for altering cell fate. Cadherin switching is also common during epithelial tumor progression, where it… CONTINUE READING