Misoprostol versus low-dose oxytocin for cervical ripening: a prospective, randomized, double-masked trial.

@article{Ferguson2002MisoprostolVL,
  title={Misoprostol versus low-dose oxytocin for cervical ripening: a prospective, randomized, double-masked trial.},
  author={James E. Ferguson and Barbara H Head and Fred H Frank and Margaret L Frank and Jeremy Singer and Theodoros J Stefos and Giancarlo Mari},
  journal={American journal of obstetrics and gynecology},
  year={2002},
  volume={187 2},
  pages={273-9; discussion 279-80}
}
OBJECTIVE A variety of cervical ripening agents exist, yet none is ideal. We performed a prospective, randomized, double-masked comparison of low-dose minimal-escalation oxytocin to misoprostol in a predominantly high-risk population. STUDY DESIGN Patients were allocated prospectively in a double-masked, randomized, stratified basis by an investigational pharmacist between December 1996 and December 2000 to receive either active intravenous oxytocin and placebo intravaginal misoprostol or… CONTINUE READING