Misoprostol in the treatment of chronic refractory constipation: results of a long-term open label trial.

BACKGROUND Misoprostol is known to be effective in stimulating intestinal transit both in healthy individuals and in patients with chronic constipation when evaluated in short-term trials. The aim of this study was to determine the utility of misoprostol in the long-term management of patients with chronic refractory constipation. METHODS Eighteen… CONTINUE READING