Misoprostol and illegal abortion in Rio de Janeiro, Brazil

  title={Misoprostol and illegal abortion in Rio de Janeiro, Brazil},
  author={Sarah H. Costa and Martin P. Vessey},
  journal={The Lancet},
We report on the determinants and consequences of induced abortion among 803 women admitted to hospital with abortion complications in Rio de Janeiro, Brazil, in 1991. 458 (57%) women reported using misoprostol to induce abortion, 74% in the first 4 months of pregnancy. Doses of 200-16,800 micrograms were reported, with a median of 800 micrograms. 65% of the women took the drug orally, 29% used a combination of oral and vaginal routes, and 6% administered it intravaginally. Vaginal bleeding and… Expand
Misoprostol: the experience of women in Fortaleza, Brazil.
Despite the current lack of safer alternatives, misoprostol does not seem a satisfactory solution to illegal abortion in Brazil. Expand
Commercial availability of misoprostol and induced abortion in Brazil
  • S. H. Costa
  • Medicine
  • International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • 1998
The experience of Brazilian women with misoprostol is an example of how women when faced with unwanted pregnancy will resort to illegal abortion whatever the costs are to their health. Expand
Vaginal misoprostol 1000 μg for early abortion
According to the observed outcomes, 1000-μg misoprostol vaginally could be a valid method to terminate pregnancies up to nine weeks gestation. Expand
Evaluation of the effectiveness of vaginal misoprostol to induce first trimester abortion.
Two doses, 200 and 400 micrograms, of misoprostol, administered vaginally every 12 hours, up to four times, were tested in 101 and 133 healthy women, respectively, for interruption of pregnanciesExpand
Post-abortion complications after interruption of pregnancy with misoprostol
It is suggested that misoprostol is a safe, inexpensive method for inducing abortion, and leads to fewer complications and consequently shorter hospital stays, and should be considered a viable option in situations where induction of abortion is legal or medically indicated. Expand
First-trimester pregnancy termination with 800 μg of vaginal misoprostol every 12 h
  • N. Salakos, A. Kountouris, +4 authors G. Creatsas
  • Medicine
  • The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
  • 2005
According to the observed outcomes, 800 μg of misoprostol vaginally could be a valid method to terminate pregnancies up to 9 weeks of gestation. Expand
[Illegal abortion with misoprostol in Guadeloupe].
The profile of the population concerned and the justifications for choosing illegal abortion by misoprostol provides elements allowing better focus of education concerning abortion, contraception and family planning. Expand
Early pregnancy termination with vaginal misoprostol before and after 42 days gestation.
The vaginal misoprostol-alone regimen is highly effective for women seeking medical abortion of pregnancies of <or=56 days, however, better efficacy may be achieved at a gestational age of <42 days. Expand
[Misoprostol teratogenicity: a prospective study in Argentina].
A cohort study compared the frequency of abortion and major congenital abnormalities in offspring of pregnant women exposed to misoprostol and an unexposed group of pregnantWomen, both groups consulting to a teratology information service, and found a significant association between prenatal exposure to misoethylene. Expand
Oral misoprostol use in early complicated pregnancy
This study demonstrates that the use of oral misoprostol is a simple, inexpensive and easy procedure for terminating early complicated pregnancies, although additional surgical evacuation of the uterus was required in the large majority of patients. Expand


Treatment by intrauterine or vaginal prostaglandins offers promise as a method of pregnancy termination which avoids much of the physical and emotional trauma associated with surgical termination, and has the advantage of not requiring hospital admission in the majority of cases. Expand
Uterine contractility and induction of abortion in early pregnancy by misoprostol and mifepristone
Findings show that misoprostol increases uterine activity in early pregnancy and suggest that, in combination with mifepristone, it may be a highly effective method of inducing therapeutic abortion. Expand
The use of prostaglandins and their analogues for abortion.
  • M. Bygdeman
  • Medicine
  • Clinics in obstetrics and gynaecology
  • 1984
In general, termination of second trimester pregnancy is associated with three to five times higher morbidity and mortality risks than termination during the first trimester and the use of prostaglandin analogues may offer important advantages, the most important one being the possibility of using non-invasive routes of administration. Expand
Wirkung des PGE1-Methylanalogons Misoprostol auf den schwangeren Uterus im ersten Trimester
The results show that the sensitivity of the human pregnant uterus to prostaglandin analogues cannot be reliably predicted from animal studies and misoprostol should not be used in human first-trimester pregnancy. Expand
Family planning among low-income women in Rio de Janeiro: 1984-1985.
A 1984-1985 survey in 7 slum communities in Rio de Janeiro Brazil found that 7% of sexually active women ages 15-49 were pregnant 20% had been contraceptively sterilized and 5% were infertile. TheExpand
2308 second trimester terminations using extra‐amniotic or intra‐amniotic prostaglandin E2: an analysis of efficacy and complications
Since long‐term complications have been assessed for this method of termination and found to be infrequent, there is no reason to consider a change in methods for second trimester terminations. Expand