Misoprostol With or Without Letrozole Pretreatment for Termination of Pregnancy: A Randomized Controlled Trial

@article{Lee2011MisoprostolWO,
  title={Misoprostol With or Without Letrozole Pretreatment for Termination of Pregnancy: A Randomized Controlled Trial},
  author={Vivian Chi Yan Lee and Ernest Hung Yu Ng and William Shu-Biu Yeung and Pak-chung Ho},
  journal={Obstetrics \& Gynecology},
  year={2011},
  volume={117},
  pages={317-323}
}
OBJECTIVE: To compare the success rate and side effects of letrozole and misoprostol versus misoprostol alone for medical termination of early pregnancy. METHODS: Patients requesting termination of pregnancy up to 63 days of gestation were randomized into two groups. The letrozole group received letrozole 10 mg daily for 3 days followed by 800 micrograms of vaginal misoprostol, while the placebo group received placebo for 3 days followed by the same dosage of misoprostol. The complete abortion… Expand

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ConditionsTubal Pregnancy
InterventionDrug, Other
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Aim of study Compare the success rate of misoprostol with versus without letrozole as a pretreatment for medical termination of pregnancy during the first trimester. Hypothesis… Expand
ConditionsMissed Abortion
InterventionDevice, Drug
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TLDR
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TLDR
The results of this pilot study suggest that a regimen of mifepristone, letrozole and misoprostol is associated with a high complete abortion rate without major adverse events. Expand
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TLDR
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