Misophonia and Potential Underlying Mechanisms: A Perspective

  title={Misophonia and Potential Underlying Mechanisms: A Perspective},
  author={Devon Beebe Palumbo and Ola Alsalman and Dirk De Ridder and Jae-Jin Song and Sven Vanneste},
  journal={Frontiers in Psychology},
There is a growing research interest in the diagnosis rate of misophonia, a condition characterized by a negative emotional/autonomic reaction to specific everyday sounds. Diagnosis of misophonia requires a thorough case history and audiological test procedures. Associative and non-associative learning models for understanding the underlying mechanisms of misophonia have been presented. Currently, there is no cure or pharmaceutical agent for misophonia; however, therapy programs addressing… 


Recent scientific studies have noted that misophonia is a complex neurophysiological and behavioural syndrome characterised by high physiological and emotional reactivity, resulting from an

Misophonia: A Systematic Review of Current and Future Trends in This Emerging Clinical Field

An analysis of the literature since 2001 identifies the most relevant aspects but also controversies, identifies the theoretical and methodological approaches, and highlights the outstanding advances until May 2022 as well as aspects that remain unknown and deserve future research efforts.

The neurobiology of misophonia and implications for novel, neuroscience-driven interventions

Decreased tolerance in response to specific every-day sounds (misophonia) is a serious, debilitating disorder that is gaining rapid recognition within the mental health community. Emerging research

Treating Adolescent Misophonia With Cognitive Behavioral Therapy: Considerations for Including Exposure

This case offers one example of misophonia being successfully treated with a cognitive-behavioral approach to treatment (including exposures) in an adolescent girl, andoretically and empirically derived recommendations for including exposure inMisophonia treatment are presented.

Understanding misophonia from an audiological perspective: a systematic review.

  • Sajana AryalP. Prabhu
  • Medicine
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • 2022
The review confirms that misophonia is a neurophysiological disorder that may border between audiology, neurology, and psychiatry, and highlights the need to include an audiologist as a team member in the evaluation and management ofmisophonia.

Toward a Multidimensional Understanding of Misophonia Using Cluster-Based Phenotyping

An exploratory k-means cluster analysis to evaluate symptom presentation in a non-clinical sample of young adult undergraduate students illustrated the spectrum characteristics of misophonia where symptom patterns range from more “pure” formmisophonia to presentations that involve more broad-range sensory-related and psychiatric symptoms.

Treatment of Misophonia with Risperidone in a Patient with Autism Spectrum Disorder

Risperidone's potential for treating misophonia may warrant systematic investigation and is likely not explained by inpatient admission alone or other simultaneous pharmacologic treatments, as the effect was seen during an isolated titration of ris peridone.

Case Report Treatment of Misophonia with Risperidone in a Patient with Autism Spectrum Disorder

The case of a 32-year-old male with autism spectrum disorder (ASD) suffering from severe misophonia is reported, where after titrating risperidone to 2mg twice a day, the patient reported a reduction in his symptoms and his AMISOS-R score dropped.

Case study of Relaxation and Counterconditioning Therapy for Misophonia: A Conditioned Aversive Reflex Disorder

The conceptualization of misophonia as a conditioned aversive reflex disorder consisting of a physical (e.g., muscle) reflex elicited by the misophonic trigger stimulus and subsequent emotional, physiological, and behavioral responses is illustrated.



‘Mastication rage’: a review of misophonia – an under-recognised symptom of psychiatric relevance?

  • G. Bruxner
  • Psychology, Medicine
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists
  • 2016
Misophonia is a symptom associated with obsessive-compulsive disorder and anxiety disorders and may be a syndrome in itself associated with significant distress and avoidance.

Hatred of sounds: misophonic disorder or just an underreported psychiatric symptom?

It is argued that misophonia is better described as a symptom of a) obsessive-compulsive disorder, b) generalized anxiety disorder, and c) schizotypal personality disorder.

A Large-Scale Study of Misophonia.

It is unlikely that another "real" underlying clinical, psychiatric, or psychological disorder can explain away the misophonia, but half of the participants reported experiencing euphoric, relaxing, and tingling sensations with particular sounds or sights, a relatively unfamiliar phenomenon called autonomous sensory meridian response (ASMR).

Misophonia: Diagnostic Criteria for a New Psychiatric Disorder

It is suggested that misophonia should be classified as a discrete psychiatric disorder and diagnostic criteria could help to officially recognize the patients and the disorder, improve its identification by professional health carers, and encourage scientific research.

Hyperacusis and misophonia: the lesser-known siblings of tinnitus.

This article attempts to educate the medical community about hyperacusis and misophonia, both of which can have devastating effects on the lives of patients, and ways to manage them.

Misophonia: incidence, phenomenology, and clinical correlates in an undergraduate student sample.

This study investigates the incidence, phenomenology, correlates, and impairment associated with misophonia symptoms in 483 undergraduate students through self-report measures and indicates potential factors that may co-occur and influence the clinical presentation of a person with misophile symptoms.

Misophonia, Phonophobia, and "Exploding Head" Syndrome

1. Misophonia, phonophobia, and “exploding head” syndrome have symptoms that may occur together with some forms of tinnitus or they can occur alone. 2. These sensations are different

Selective sound sensitivity syndrome (misophonia) in a patient with Tourette syndrome.

  • M. NealA. Cavanna
  • Psychology, Medicine
    The Journal of neuropsychiatry and clinical neurosciences
  • 2013
This is the first documented case of misophonia reported by a patient with a diagnosis of Tourette syndrome, and there is the possibility that systematic screening for Misophonia in TS might reveal a pathophysiological association.

Misophonia: physiological investigations and case descriptions

It is shown that misophonia is a disorder that produces distinct autonomic effects not seen in typically developed individuals, and heightened ratings and skin conductance responses to auditory, but not visual stimuli, relative to a group of typically developed controls.