Misonidazole: inter-related factors affecting cytotoxicity.

  title={Misonidazole: inter-related factors affecting cytotoxicity.},
  author={Cameron J. Koch and Robert L Howell},
  journal={International journal of radiation oncology, biology, physics},
  volume={8 3-4},
A detailed investigation was undertaken of reported modifiers of the toxicity towards hypoxic cells of misonidazole. The modifiers tested were medium type, cell type, cell density, concentration of misonidazole, addition of serum, addition of sulfhydryl, addition of oxygen and pH. The latter 5 modifiers were found to be most important and were studied in… CONTINUE READING