Mismatch repair status and high expression of PD-L1 in nasopharyngeal carcinoma

@inproceedings{Zhao2019MismatchRS,
  title={Mismatch repair status and high expression of PD-L1 in nasopharyngeal carcinoma},
  author={Liang Zhao and Xiyi Liao and Ganji Hong and Yanzhen Zhuang and Kaili Fu and Peiqiong Chen and Yuhuan Wang and Haojun Chen and Qin Lin},
  booktitle={Cancer management and research},
  year={2019}
}
Purpose To analyze the mismatch repair (MMR) status and PD-L1 expression in nasopharyngeal carcinoma (NPC), and investigate whether PD-L1 and MMR status could be used as a biomarker for predicting response of immune checkpoint blockades (ICBs) treatment. Patients and methods A total of 108 patients were initially histopathologically diagnosed with NPC between December 2017 and September 2018. All tissue specimens were collected before any treatment. Tumor tissue MMR status was determined by… CONTINUE READING

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