Misleading effects of clonazepam in symptomatic electrical status epilepticus during sleep syndrome.

@article{BahiBuisson2006MisleadingEO,
  title={Misleading effects of clonazepam in symptomatic electrical status epilepticus during sleep syndrome.},
  author={Nadia Bahi-Buisson and Rosanna Savini and Monica Eisermann and Christine Bulteau and Olivier Dulac and Lucie Hertz-Pannier and Catherine Chiron},
  journal={Pediatric neurology},
  year={2006},
  volume={34 2},
  pages={
          146-50
        }
}
Electrical status epilepticus during sleep syndrome and its variants are age-dependent epileptic encephalopathies associated with a sleep-related electroencephalographic pattern of continuous spike-waves, combined with motor or cognitive impairment. These epileptic encephalopathies are usually not responsive to conventional antiepileptic drugs. This report describes two children in whom clonazepam had no effect on cognitive and motor disorders but controlled spike activity, preventing a proper… CONTINUE READING