Misinterpretation of the Determinants of Elevated Forward Wave Amplitude Inflates the Role of the Proximal Aorta.

@article{Phan2016MisinterpretationOT,
  title={Misinterpretation of the Determinants of Elevated Forward Wave Amplitude Inflates the Role of the Proximal Aorta.},
  author={Timothy S. Phan and John K-J. Li and Patrick Segers and Julio A. Chirinos},
  journal={Journal of the American Heart Association},
  year={2016},
  volume={5 2}
}
BACKGROUND The hemodynamic basis for increased pulse pressure (PP) with aging remains controversial. The classic paradigm attributes a predominant role to increased pulse wave velocity (PWV) and premature wave reflections (WRs). A controversial new paradigm proposes increased forward pressure wave amplitude (FWA), attributed to proximal aortic characteristic impedance (Zc), as the predominant factor, with minor contributions from WRs. Based on theoretical considerations, we hypothesized that… CONTINUE READING
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Wave (Re-)reflection and pulse wave velocity determine forward wave amplitude and morphology (abstract)

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