Misinterpretation of elevated blood diastase due to impaired renal clearance.

@article{Sachar1956MisinterpretationOE,
  title={Misinterpretation of elevated blood diastase due to impaired renal clearance.},
  author={L. Sachar and R. Weinhaus},
  journal={A.M.A. archives of surgery},
  year={1956},
  volume={73 2},
  pages={
          305-8
        }
}
Introduction It has been previously pointed out that the blood diastase values may be elevated in patients with diseases other than acute pancreatitis.* Somogyi1considered the normal range of blood diastase to be between 60 and 200 units per 100 ml. of serum. However, in a study of the serum amylase of all admissions to a general hospital. Heifetz, Sicher, and Sachar found that about 10% of the patients had blood diastase values above 200 at the time of their entry into the hospital. This is… Expand
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References

SHOWING 1-4 OF 4 REFERENCES
DIASTATIC ACTIVITY OF HUMAN BLOOD
TLDR
The presence of diastase in human blood was first noted in 18462 and subsequently the enzyme was found to be a normal constituent of mammalian blood in general and its origin was traced to the blood. Expand
Relationship Between Blood Amylase and Urinary Amylase in Man
Somogyi 1 has shown that the amylase content in the blood is rather constant for the individual, while the variations from individual to individual are considerable. The study of the amylase contentExpand
Acute pancreatitis and the laboratory.
  • R. Elman
  • Medicine
  • Surgery, gynecology & obstetrics
  • 1955