Misdirected Sympathy: The Role of Sympatholysis in Sepsis and Septic Shock.

@article{Ferreira2018MisdirectedST,
  title={Misdirected Sympathy: The Role of Sympatholysis in Sepsis and Septic Shock.},
  author={Jason A Ferreira and Brittany D Bissell},
  journal={Journal of intensive care medicine},
  year={2018},
  volume={33 2},
  pages={
          74-86
        }
}
The spectrum of sepsis and septic shock remains a highly prevalent disease state, carrying a high risk of morbidity and mortality. The sympathetic nervous system (SNS) plays an important role in this initial cascade, enabling the host to respond to invading pathogens; however, prolonged activation can become pathological. The potential for unregulated sympathetic tone to become of detriment in patients with sepsis has fueled interest in the role and impact of sympatholysis, the selective… CONTINUE READING
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