Misclassification of dysplasia in patients with inflammatory bowel disease: consequences for progression rates to advanced neoplasia.

@article{Schaik2011MisclassificationOD,
  title={Misclassification of dysplasia in patients with inflammatory bowel disease: consequences for progression rates to advanced neoplasia.},
  author={Fiona D. M. van Schaik and Fiebo J. W. ten Kate and George Johan Arnold Offerhaus and Marguerite E. I. Schipper and Frank Paul Vleggaar and Christien Janneke van der Woude and Pieter C. F. Stokkers and Dirk J de Jong and Daniel W. Hommes and A A van Bodegraven and Peter D. Siersema and Bas Oldenburg},
  journal={Inflammatory bowel diseases},
  year={2011},
  volume={17 5},
  pages={
          1108-16
        }
}
BACKGROUND The natural behavior of flat low-grade (LGD) and indefinite dysplasia (IND) in patients with inflammatory bowel disease (IBD) remains uncertain and seems to be dependent on the interpretation of the pathologist. We studied the progression rate of flat LGD and IND to advanced neoplasia (high-grade dysplasia [HGD] or colorectal cancer [CRC]) before and after histopathological review by a panel of gastrointestinal expert pathologists. METHODS A nationwide pathology database was used… CONTINUE READING