Mirtazapine-Associated Urinary Retention

  title={Mirtazapine-Associated Urinary Retention},
  author={P. Oulis and Athanasios Leonardos and G. Koulouris and G. Konstantakopoulos},
  journal={Journal of Neuropsychiatry and Clinical Neurosciences},
To the Editor: Mirtazapine, an efficacious antidepressant of dual noradrenergic and serotoninergic mechanisms of action, is deemed particularly safe and well tolerated, especially with respect to its urinary side effects, owing to its very weak muscarinic anticholinergic properties. 1 Moreover, it has been found to ameliorate l-dopainduced dyskinesias in patients with Parkinson’s disease. 2 Its safety in this respect makes it an attractive choice for the treatment of depression in elderly male… Expand
1 Citations
Inhibition effects of some antidepressant drugs on pentose phosphate pathway enzymes.
It was found that aripiprazole, mirtazapine, risperidone, escitalopram and haloperidol show effective inhibitor properties on purified G6PD and 6PGD enzymes. Expand


Mirtazapine in l-Dopa-Induced Dyskinesias
The antidyskinetic properties of mirtazapine proved to be moderately effective in reducing l-dopa-induced dyskinesias, either alone or in association with amantadine, and may be of use in patients who do not respond or are intolerant to amanadine. Expand
Successful treatment of reboxetine-induced urinary hesitancy with tamsulosin
A series of case studies in which tamsulosin has been successfully used in the management of urinary hesitancy during therapy with the selective noradrenaline reuptake inhibitor reboxetine for major depressive disorder (MDD). Expand
Urinary Side Effects of Duloxetine in the Treatment of Depression and Stress Urinary Incontinence.
Duloxetine treatment in women and men with depression and in women with SUI was rarely associated with obstructive voiding symptoms, and no subjects had objective acute urinary retention requiring catheterization. Expand
Review of the results from clinical studies on the efficacy, safety and tolerability of mirtazapine for the treatment of patients with major depression.
Mirtazapine is a unique addition to the antidepressant armamentarium as first-line therapy in patients with major depression and symptoms of anxiety/agitation or anxiety/somatization or complaints of insomnia and as a useful alternative in depressed patients who do not adequately respond to or are intolerant of tricyclic antidepressants or serotonin-specific reuptake inhibitors. Expand
Sonographic assessment of urinary retention in multiple system atrophy and idiopathic Parkinson's disease
  • K. Hahn, G. Ebersbach
  • Medicine
  • Movement disorders : official journal of the Movement Disorder Society
  • 2005
Sonography of the bladder was performed before and after voluntary voiding in 20 subjects with possible/probable multiple system atrophy (MSA), 20 patients with idiopathic Parkinson's disease (PD), and 20 healthy controls to assess for urinary retention. Expand