Mirtazapine, a sedating antidepressant, and improved driving safety in patients with major depressive disorder: a prospective, randomized trial of 28 patients.


OBJECTIVE The objectives of the study were to investigate the effects of mirtazapine, a sedating antidepressant, on driving safety in major depressive disorder (MDD) patients and to observe the effect of mirtazapine on daytime alertness. METHOD Twenty-eight patients who met the DSM-IV criteria for MDD completed the study in a university teaching hospital… (More)