Mipu1 overexpression protects macrophages from oxLDL-induced foam cell formation and cell apoptosis.

@article{Qu2014Mipu1OP,
  title={Mipu1 overexpression protects macrophages from oxLDL-induced foam cell formation and cell apoptosis.},
  author={Shun-Lin Qu and Wen-jing Fan and Chi Zhang and Fang Guo and Dan Han and Wen-jun Pan and Wei Li and Da-ming Feng and Zhisheng Jiang},
  journal={DNA and cell biology},
  year={2014},
  volume={33 12},
  pages={839-46}
}
Mipu1 (myocardial ischemic preconditioning upregulated protein 1) is a novel N-terminal Kruppel-associated box (KRAB)/C2H2 zinc finger superfamily protein, that displays a powerful effect in protecting H9c2 cells from oxidative stress-induced cell apoptosis. The present study aims to investigate the effect of Mipu1 overexpression on oxidized low-density lipoprotein (oxLDL)-induced foam cell formation, cell apoptosis, and its possible mechanisms. New Zealand healthy rabbits were used to… CONTINUE READING
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