Mionecrosis, hemorragia y edema inducidos por el veneno de Bothrops asper en ratón blanco

@article{Gutirrez1980MionecrosisHY,
  title={Mionecrosis, hemorragia y edema inducidos por el veneno de Bothrops asper en rat{\'o}n blanco},
  author={Jos{\'e} Mar{\'i}a Guti{\'e}rrez and Olga P{\'e}rez Arroyo and Ronald Eduardo D{\'i}az Bola{\~n}os},
  journal={Toxicon},
  year={1980},
  volume={18},
  pages={603-610}
}
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112 Citations
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112 Citations

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Estudio ultraestructural de la mionecrosis inducida en raton por el veneno de terciopelo (Bothrops asper) de Costa Rica
Pathogenesis of myonecrosis induced by crude venom and a myotoxin of Bothrops asper.
Neutralizacion de los efectos locales del veneno de Bothrops asper por un antiveneno polivalente
Quantitation of myonecrosis induced by myotoxin a from prairie rattlesnake (Crotalus viridis viridis) venom.
Histopathological and biochemical alterations induced by intramuscular injection of Bothrops asper (terciopelo) venom in mice.
Características bioquímicas y evaluación preclínica de un antiveneno botrópico liofilizado contra el veneno de la serpiente Bothrops atrox
TLDR
It is concluded that the investigated product complies with the World Health Organization (WHO) requirements to be considered an effective antivenom capable of neutralizing the main biological activities previously mentioned.
Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom.
Tabebuia aurea decreases inflammatory, myotoxic and hemorrhagic activities induced by the venom of Bothrops neuwiedi.
Muscle necrosis and regeneration after envenomation by Bothrops jararacussu snake venom.
Experimental pathology of local tissue damage induced by Bothrops asper snake venom.
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References

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TLDR
Myonecrotic effect of rattlesnake venom on mouse skeletal muscle was studied and may serve as a useful model for studying muscle necrosis because of its rapid onset and relative ease of induction.
Myonecrosis induced by rattlesnake venom. An electron microscopic study.
TLDR
Myonecrotic effect of rattlesnake venom on mouse skeletal muscle was studied and may serve as a useful model for studying muscle necrosis because of its rapid onset and relative ease of induction.
Hemorrhagic toxins from rattlesnake (Crotalus atrox) venom. Pathogenesis of hemorrhage induced by three purified toxins.
TLDR
The experimental injection of three purified hemorrhagic toxins induced hemorrhage by the same mechanism as does the crude venom, ie, per rhexis, in addition, one of the toxins, hemorrhagic toxin beta, causes myonecrosis.
Isolation of myotoxic component from rattlesnake (Crotalus viridis viridis) venom. Electron microscopic analysis of muscle damage.
TLDR
The pathogenesis of myonecrosis induced by a purified component of rattlesnake (Crotalus viridis viridis) venom was studied at the light and electron microscopic levels, with the pure component altered skeletal muscle cells specifically, withThe sarcoplasmic reticulum being the primary site of action.
Morphology of local tissue damage in experimental snake envenomation.
  • M. Homma, A. Tu
  • Medicine, Biology
    British journal of experimental pathology
  • 1971
TLDR
Local lesions due to i.m. injection of snake venoms were investigated and it was confirmed that the venoms containing both myonecrogenetic and haemorrhagic activity, crotaline and viperine venoms, are liable to damage the arteries, and that the elapid venoms do not produce significant changes in the arterial walls.
Toxicologic study of snake venoms from Costa Rica.
THE SURGICAL TREATMENT OF SNAKE BITES
Fractionation of Sakishima-habu (Trimeresurus elegans) Venom and Lethal, Hemorrhagic, and Edema-Forming Activities of the Fractions
Pathological studies on Habu-snake bite