Mint3 potentiates TLR3/4- and RIG-I-induced IFN-β expression and antiviral immune responses.

Abstract

Type I IFNs (IFN-α/β) play crucial roles in the elimination of invading viruses. Multiple immune cells including macrophages recognize viral infection through a variety of pattern recognition receptors, such as Toll-like receptors (TLRs) and retinoic acid-inducible gene-I (RIG-I)-like receptors, and initiate type I IFN secretion and subsequent antiviral… (More)

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Cite this paper

@article{Huai2016Mint3PT, title={Mint3 potentiates TLR3/4- and RIG-I-induced IFN-β expression and antiviral immune responses.}, author={Wanwan Huai and Hui Song and Zhongxia Yu and Wenwen Wang and Lihui Han and Takeharu Sakamoto and Motoharu Seiki and Lining Zhang and Qunye Zhang and Wei Zhao}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2016}, volume={113 42}, pages={11925-11930} }