Minocycline-induced lupus: clinical features and response to rechallenge.

  title={Minocycline-induced lupus: clinical features and response to rechallenge.},
  author={Thomas M Lawson and Nick Amos and D Y Bulgen and Brian D. Williams},
  volume={40 3},
OBJECTIVE To describe the spectrum of clinical features in patients with minocycline-induced lupus (MIL) and determine their response to rechallenge. METHODS The clinical features and laboratory findings of 23 patients with MIL were recorded. Ten patients were rechallenged, and their C-reactive protein (CRP) levels were monitored. RESULTS All subjects complained of polyarthralgia; three had metacarpophalangeal and proximal interphalangeal joint synovitis and one had bilateral knee effusions… CONTINUE READING
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