Minocycline-ethylenediaminetetraacetate lock solution for the prevention of implantable port infections in children with cancer.

@article{Chatzinikolaou2003Minocyclineethylenediaminet,
  title={Minocycline-ethylenediaminetetraacetate lock solution for the prevention of implantable port infections in children with cancer.},
  author={Ioannis Chatzinikolaou and Theodore F. Zipf and Hend Hanna and Jan Umphrey and Willaim Roberts and Robert J. Sherertz and Ray Y. Hachem and Issam Raad},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2003},
  volume={36 1},
  pages={116-9}
}
In this prospective cohort study, minocycline-ethylenediaminetetraacetate (M-EDTA) was used as a lock solution in indwelling ports inserted in 14 children with cancer. No port infections, thrombotic events, or other adverse events were observed, compared with 10 port infections that occurred in 48 control patients whose ports were flushed with heparin. M-EDTA is a promising lock solution in long-term catheters. 
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