Mink with Aleutian disease have high-affinity antiviral antibodies.

  title={Mink with Aleutian disease have high-affinity antiviral antibodies.},
  author={Bent Aasted and Marshall E. Bloom},
  journal={Scandinavian journal of immunology},
  volume={19 5},
Mink persistently infected with Aleutian disease virus (ADV) develop plasmacytosis (hypergammaglobulinaemia) and immune complex disease. Mink of different colour phases were infected with different strains of ADV and bled at different times after infection. The average antibody affinities (Kav) were measured in the sera and found to fall in the range of 2 X 10(9) - 2 X 10(10) M-1, thus indicating good-quality antibodies. In sera of non-Aleutian genotype mink a decline in Kav during development… CONTINUE READING