Minispectrometer with handheld probe for 5-ALA based fluorescence-guided surgery of brain tumors: Preliminary study for clinical applications.

@article{Cornelius2017MinispectrometerWH,
  title={Minispectrometer with handheld probe for 5-ALA based fluorescence-guided surgery of brain tumors: Preliminary study for clinical applications.},
  author={Jan Fr{\'e}d{\'e}rick Cornelius and Jens Placke and Johannes Knipps and Igor Fischer and Marcel A Kamp and Hans Jakob Steiger},
  journal={Photodiagnosis and photodynamic therapy},
  year={2017},
  volume={17},
  pages={147-153}
}
INTRODUCTION Recently a mini-spectrometer with a handheld probe quantifying 5-aminolevulinic acid (5-ALA) based fluorescence intensity of brain tumors was developped by Kim et al. to improve fluorescence-guided neurosurgery. OBJECTIVE To evaluate if this new tool is capable to discriminate nuances of fluorescence intensity of strongly fluorescing tumors (glioblastomas (GBM) and meningiomas (MM)). To study different modes of measurement (touch/no-touch). To determine protoporphyrin IX (PPIX… CONTINUE READING