Minireview: beta-cell replacement therapy for diabetes in the 21st century: manipulation of cell fate by directed differentiation.

Abstract

Pancreatic beta-cell failure underlies type 1 diabetes; it also contributes in an essential way to type 2 diabetes. beta-Cell replacement is an important component of any cure for diabetes. The current options of islet and pancreas transplantation are not satisfactory as definitive forms of therapy. Here, we review strategies for induced de novo pancreatic… (More)
DOI: 10.1210/me.2009-0311

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Cite this paper

@article{Yechoor2010MinireviewBR, title={Minireview: beta-cell replacement therapy for diabetes in the 21st century: manipulation of cell fate by directed differentiation.}, author={Vijay K. Yechoor and Lawrence C B Chan}, journal={Molecular endocrinology}, year={2010}, volume={24 8}, pages={1501-11} }