Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors.

@article{Lee2003MinireviewLM,
  title={Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors.},
  author={C H Lee and Peter Olson and Ronald M Evans},
  journal={Endocrinology},
  year={2003},
  volume={144 6},
  pages={2201-7}
}
Lipid and carbohydrate homeostasis in higher organisms is under the control of an integrated system that has the capacity to rapidly respond to metabolic changes. The peroxisome proliferator-activated receptors (PPARs) are nuclear fatty acid receptors that have been implicated to play an important role in obesity-related metabolic diseases such as hyperlipidemia, insulin resistance, and coronary artery disease. The three PPAR subtypes, alpha, gamma, and delta, have distinct expression patterns… CONTINUE READING
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Novel tricyclic- -alkyloxyphenylpropionic acids: dual PPAR / agonists with hypolipidemic and antidiabetic activity

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