Minireview: Gut peptides regulating satiety.

  title={Minireview: Gut peptides regulating satiety.},
  author={Maralyn Druce and Caroline J. Small and Stephen R. Bloom},
  volume={145 6},
The gastrointestinal tract and the pancreas release hormones regulating satiety and body weight. Ghrelin stimulates appetite, and glucagon-like peptide-1, oxyntomodulin, peptide YY, cholecystokinin, and pancreatic polypeptide inhibit appetite. These gut hormones act to markedly alter food intake in humans and rodents. Obesity is the current major cause of premature death in the United Kingdom, killing almost 1000 people per week. Worldwide, its prevalence is accelerating. There is currently no… CONTINUE READING
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