Mining the National Cancer Institute's tumor-screening database: identification of compounds with similar cellular activities.

@article{Rabow2002MiningTN,
  title={Mining the National Cancer Institute's tumor-screening database: identification of compounds with similar cellular activities.},
  author={Alfred A. Rabow and Robert H. Shoemaker and Edward A. Sausville and David G. Covell},
  journal={Journal of medicinal chemistry},
  year={2002},
  volume={45 4},
  pages={818-40}
}
In an effort to enhance access to information available in the National Cancer Institute's (NCI) anticancer drug-screening database, a new suite of Internet accessible (http://spheroid. ncifcrf.gov) computational tools has been assembled for self-organizing map-based (SOM) cluster analysis and data visualization. A range of analysis questions were initially addressed to evaluate improvements in SOM cluster quality based on the data-conditioning procedures of Z-score normalization, capping, and… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

Similar Papers

Loading similar papers…