Mining cross-graph quasi-cliques in gene expression and protein interaction data

  title={Mining cross-graph quasi-cliques in gene expression and protein interaction data},
  author={Jian Pei and Daxin Jiang and Aidong Zhang},
  journal={21st International Conference on Data Engineering (ICDE'05)},
A protein is the product of a gene. From the gene expression data, we can find co-expressed genes, which are groups of genes that demonstrate coherent patterns on samples. On the other hand, from the protein interaction data, we can find groups of proteins that frequently interact with each other. If we can conduct a joint mining of both gene expression data and protein interaction data, then we may find the clusters of genes that are co-expressed and also their proteins interact. Such clusters… CONTINUE READING
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