Minimum Conflict Individual Haplotyping from SNP Fragments and Related Genotype

@inproceedings{Zhang2006MinimumCI,
  title={Minimum Conflict Individual Haplotyping from SNP Fragments and Related Genotype},
  author={Xiang-Sun Zhang and Rui-Sheng Wang and Ling-Yun Wu and Wei Zhang},
  booktitle={Evolutionary bioinformatics online},
  year={2006}
}
The Minimum Error Correction (MEC) is an important model for haplotype reconstruction from SNP fragments. However, this model is effective only when the error rate of SNP fragments is low. In this paper, we propose a new computational model called Minimum Conflict Individual Haplotyping (MCIH) as an extension to MEC. In contrast to the conventional approaches, the new model employs SNP fragment information and also related genotype information, thereby a high accurate inference can be expected… CONTINUE READING