Minimizing interferences in the quantitative multielement analysis of trace elements in biological fluids by inductively coupled plasma mass spectrometry.

@article{Hsiung1997MinimizingII,
  title={Minimizing interferences in the quantitative multielement analysis of trace elements in biological fluids by inductively coupled plasma mass spectrometry.},
  author={C S Hsiung and J de S Andrade and R{\'e}mi Costa and K. Owen Ash},
  journal={Clinical chemistry},
  year={1997},
  volume={43 12},
  pages={2303-11}
}
The determination of trace and ultratrace elements in biological fluids, including urine and serum, by inductively coupled plasma mass spectrometry (ICP-MS) is discussed. Nonspectral interferences and their corrections by external calibration and calibrator addition are discussed in detail. External calibration with internal calibration and dilution is mostly sufficient to correct for encountered biological matrix effects. For some elements, such as Cs and Zn, the use of calibrator addition… CONTINUE READING
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