Minimization of recombinant human Flt3 ligand aggregation at the Tm plateau: a matter of thermal reversibility.

Abstract

This study elucidates the importance of thermal reversibility as it pertains to the minimization of recombinant human Flt3 ligand aggregation and its potential role for determining solution conditions that can achieve the greatest long-term storage stability. Both thermal reversibility and Tm were evaluated as microcalorimetric parameters of stability… (More)

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