Minimising the risk of device infection in penile prosthetic surgery: a UK perspective

  title={Minimising the risk of device infection in penile prosthetic surgery: a UK perspective},
  author={M. Elmussareh and J. Goddard and D. Summerton and T. Terry},
  journal={Journal of Clinical Urology},
  pages={280 - 288}
We have reviewed articles published on penile prosthetic infection in Medline and EMBASE databases from 2000 to 2012 with the intention of signposting ‘best evidence’ for the UK prosthetic implanter. Using the Oxford Centre for Evidence-based Medicine Levels of Evidence (LE), no paper exceeded an LE of 2b and the majority were LE 4 (case series) and LE 5 (expert opinion). This is not surprising from a UK perspective since HES data for 2009 to 2010 reported 263 penile prosthetic surgeries… Expand
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Penile prosthesis implantation is the gold standard of surgical therapy for patients with medication-refractory erectile dysfunction. However, this umbrella definition includes significantExpand


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There is no statistically significant difference in the infection rate when the scrotal and infrapubic approaches to inflatable penile prosthesis insertion are compared, and this study indicates that the rate of infection in 380 consecutive organically impotent men implanted with a Mentor Alpha I inflatable prosthesis is unchanged. Expand
Risk of infection with an antibiotic coated penile prosthesis at device replacement for mechanical failure.
The data suggest that an antibiotic coated inflatable penile prosthesis (InhibiZone) may lead to decreased infection rates in patients undergoing peniles prosthesis replacement for mechanical failure. Expand
Risk factors for penile prosthetic infection.
  • J. Jarow
  • Medicine
  • The Journal of urology
  • 1996
The risk of infection is significantly greater when penile reconstruction is required, and appears to be related to increased duration of surgery. Expand
Infectious complications of penile prosthesis surgery.
Ten patients with 9 infected prosthesis became infected after dental procedures and the need for routine antibiotic prophylaxis in the penile prosthesis patient is emphasized. Expand
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Penile prosthesis infections
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Treatment alternatives for the infected penile implant
  • J. Mulcahy
  • Medicine
  • International Journal of Impotence Research
  • 2003
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Infection reduction using antibiotic-coated inflatable penile prosthesis.
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