Minimising the risk of device infection in penile prosthetic surgery: a UK perspective

@article{Elmussareh2013MinimisingTR,
  title={Minimising the risk of device infection in penile prosthetic surgery: a UK perspective},
  author={M. Elmussareh and J. Goddard and D. Summerton and T. Terry},
  journal={Journal of Clinical Urology},
  year={2013},
  volume={6},
  pages={280 - 288}
}
We have reviewed articles published on penile prosthetic infection in Medline and EMBASE databases from 2000 to 2012 with the intention of signposting ‘best evidence’ for the UK prosthetic implanter. Using the Oxford Centre for Evidence-based Medicine Levels of Evidence (LE), no paper exceeded an LE of 2b and the majority were LE 4 (case series) and LE 5 (expert opinion). This is not surprising from a UK perspective since HES data for 2009 to 2010 reported 263 penile prosthetic surgeries… Expand
Infection of Penile Prostheses in Patients with Diabetes Mellitus.
TLDR
Strong evidence exists that the risk of penile prosthesis infection has reduced over the decades with device improvement and surgical expertise. Expand
Penile Prosthesis Infections-A Review of Risk Factors, Prevention, and Treatment.
TLDR
The pathophysiology of infections is described, evidence associating clinical risk factors with IPP infection is examined, benefits of techniques aimed at preventing and managing infection are assessed, and future directions are discussed. Expand
Penile Prosthesis Salvage: Review of Past and Current Practices
TLDR
This review highlights landmark studies and recent literature regarding penile implant salvage in the setting of infection and examines use of temporary intracorporal antibiotic-infused calcium sulfate paste in theSetting of implant salvage. Expand
Comparing Risk Factors for Adverse Outcomes in Virgin Inflatable Penile Prosthesis Implantations and Revisions: A Retrospective Cohort Study
TLDR
The rate of postoperative infection for all patients undergoing IPP was found to be 8.20%, a higher estimate than historically recorded and to varying degrees, smoking, concomitant procedures, and DM were associated with adverse operative outcomes. Expand
Updates in penile prosthesis infections
TLDR
The current state of knowledge surrounding penile prosthesis infections is reviewed, with attention to the evidence for methods to prevent infection and best practices for device reimplantation. Expand
Infection Prevention Strategies Prior to Penile Implant Surgery.
TLDR
Current approaches to infection prevention include careful patient selection and preoperative evaluation, broad-spectrum antimicrobial prophylaxis, and modifications to surgical technique that minimize skin contact and postoperative hematoma formation. Expand
Advances in Infection Prevention Strategies for Penile Prosthesis Surgery
TLDR
Although significant strides have been made in reducing penile prosthesis infections, further education and research efforts are needed to continue to prevent this infrequent, but devastating complication, a review discusses recent advances in penile infection understanding and prevention. Expand
Risk profiling in patients undergoing penile prosthesis implantation
Penile prosthesis implantation is the gold standard of surgical therapy for patients with medication-refractory erectile dysfunction. However, this umbrella definition includes significantExpand

References

SHOWING 1-10 OF 68 REFERENCES
Does surgical approach affect the incidence of inflatable penile prosthesis infection?
TLDR
There is no statistically significant difference in the infection rate when the scrotal and infrapubic approaches to inflatable penile prosthesis insertion are compared, and this study indicates that the rate of infection in 380 consecutive organically impotent men implanted with a Mentor Alpha I inflatable prosthesis is unchanged. Expand
Risk of infection with an antibiotic coated penile prosthesis at device replacement for mechanical failure.
TLDR
The data suggest that an antibiotic coated inflatable penile prosthesis (InhibiZone) may lead to decreased infection rates in patients undergoing peniles prosthesis replacement for mechanical failure. Expand
Risk factors for penile prosthetic infection.
  • J. Jarow
  • Medicine
  • The Journal of urology
  • 1996
TLDR
The risk of infection is significantly greater when penile reconstruction is required, and appears to be related to increased duration of surgery. Expand
Infectious complications of penile prosthesis surgery.
TLDR
Ten patients with 9 infected prosthesis became infected after dental procedures and the need for routine antibiotic prophylaxis in the penile prosthesis patient is emphasized. Expand
Dilemmas of inflatable penile prosthesis revision surgery: what practices achieve the best outcomes and the lowest infection rates? (CME).
TLDR
Penile prosthesis revision in a clinically uninfected patient has a higher infection rate than a first-time implantation, so the combination of infection-retardant coated components, vigorous washout, proper preparation of skin incision site, use of perioperative antibiotics, and avoiding contact between the patient's skin and the implant will lower infection rates. Expand
Penile prosthesis cultures during revision surgery: a multicenter study.
TLDR
The majority of clinically uninfected penile prostheses have organisms growing in the implant spaces at reoperation, most of these organisms are staphylococcal species that are sensitive to rifampin/minocycline. Expand
Inflatable penile implant infection: predisposing factors and treatment suggestions.
TLDR
The etiology of impotence as a predisposition for infection in primary implantations was significant for spinal cord injury and steroid use, and staphylococcus species were the most commonly cultured organisms. Expand
Penile prosthesis infections
TLDR
There were no statistically significant differences in infection rates between first time and repeat prosthesis recipients and between diabetic and non-diabetic recipients. Expand
Treatment alternatives for the infected penile implant
  • J. Mulcahy
  • Medicine
  • International Journal of Impotence Research
  • 2003
TLDR
This approach is less likely to succeed when the infection is manifest soon (weeks) after the placement procedure, is accompanied by extensive cellulitis and is caused by virulent organisms. Expand
Infection reduction using antibiotic-coated inflatable penile prosthesis.
TLDR
InhibiZone-coated IPPs showed a statistically significant reduction in infection in virgin nondiabetic, virgin diabetic, and revision with washout implants, compared with previous publications of infection rates with noncoated implants. Expand
...
1
2
3
4
5
...