Minimising the effects of bolus dispersion in bolus-tracking MRI.

  title={Minimising the effects of bolus dispersion in bolus-tracking MRI.},
  author={Lisa Willats and Alan Connelly and Fernando Calamante},
  journal={NMR in biomedicine},
  volume={21 10},
Bolus-tracking perfusion measurements in patients with vascular abnormalities are often unreliable, because delay and/or dispersion of the bolus within the vessels distorts the measured arterial input function (AIF). Erroneous measurements of perfusion can be identified by examining the measured response function, the shape of which is determined by both the tissue and arterial retention. In this work, an accurate response function is extracted by combining maximum-likelihood expectation… CONTINUE READING
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