Minimal protection of the liver by ischemic preconditioning in pigs.

@article{Schulz2001MinimalPO,
  title={Minimal protection of the liver by ischemic preconditioning in pigs.},
  author={Richard Schulz and Martin Karl Walz and Matthias Behrends and Tobias Neumann and guido. gerken and Gerd Heusch},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2001},
  volume={280 1},
  pages={H198-207}
}
Ischemic preconditioning (IP) protects the rat liver. In pigs, in which hepatic tolerance to ischemia is similar to that in humans, information on IP is lacking. Therefore, in enflurane-anesthetized pigs, hepatic vessels were occluded for 120 min (protocol 1) or 200 min (protocol 2) without (control) and with IP (3 times 10 min ischemia-reperfusion each). In protocol 1, cumulative bile flow (CBF) during reperfusion was greater in IP (47.3 +/- 5.2 ml/8 h) than in control (17.1 +/- 7.8 ml/8 h, P… CONTINUE READING