Minimal-model estimates of insulin sensitivity are insensitive to errors in glucose effectiveness.

Abstract

The minimal-model method allows for estimation of insulin sensitivity (S(I) = P(3)/P(2)) and glucose effectiveness (S(G) = P(1)) from the time course of glucose and insulin after a glucose bolus. We previously demonstrated that the minimal-model results in overestimates of S(G) in subjects with normal insulin secretory function. To determine whether… (More)

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Cite this paper

@article{McDonald2000MinimalmodelEO, title={Minimal-model estimates of insulin sensitivity are insensitive to errors in glucose effectiveness.}, author={Cullen McDonald and Andrea Dunaif and Diane T. Finegood}, journal={The Journal of clinical endocrinology and metabolism}, year={2000}, volume={85 7}, pages={2504-8} }